Kidney transplantation involves an operation to place a new kidney inside your body to take over the work of your failed kidneys. The kidney may come from someone who was died (cadaver donor) or from a living donor who may be a close relative, friend, or possibly a stranger who wished to dominate the kidney to anyone in need of a transplant (non-directed donor). With a transplant, you need to take medications every day to prevent your body from recognizing the new kidney as “foreign” and rejecting it. Your doctor will help you to decide which of these options is best for you.